Antiphospholipid Syndrome Overview
Antiphospholipid Syndrome (APS) is an autoimmune disorder in which the body produces abnormal antibodies that mistakenly attack phospholipids — essential components of cell membranes and blood-clotting systems. This triggers excessive blood clotting, known as thrombosis, which can block arteries and veins, leading to serious complications.
APS can affect anyone but is most common in women of childbearing age. It is a major cause of recurrent miscarriages, stroke, and deep vein thrombosis (DVT) in young adults. APS may occur on its own (primary APS) or in connection with another autoimmune condition such as lupus (SLE) — this is called secondary APS.
Antiphospholipid Syndrome Symptoms vary but may include:
- Blood clots in legs (DVT) or lungs (pulmonary embolism)
- Stroke or transient ischaemic attacks (TIAs)
- Recurrent pregnancy loss
- Low platelet count
- Skin rash (livedo reticularis)
- Heart valve issues (valvular thickening or damage0029
Preventing Clotting
APS is a lifelong condition, but with proper management, many people lead full, healthy lives. Early diagnosis and prevention of clotting events are key.
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Risks and Complications of Amniocentesis
Treatment for Antiphospholipid Syndrome
