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Causes of Cyclothymia

Researcher examining brain scans on a computer to study neurological causes of cyclothymia

A medical professional analyses brain imaging results to explore potential neurological links to cyclothymia.

Causes of Cyclothymia

Causes of cyclothymia are not entirely understood. However, research points to a complex interaction between genetic, biological, psychological, and environmental factors. Like other mood disorder. Likewise, cyclothymia tends to run in families and may be linked to irregularities in brain chemistry and structure. Understanding these risk factors helps inform treatment strategies and supports early intervention for those at risk.

Genetic Influences

A strong hereditary component is often present in cases of cyclothymia:

Individuals with a family history of bipolar disorder, depression, or other mood conditions are more likely to develop cyclothymia

Twin studies suggest a moderate genetic link, although researchers have not identified a single “cyclothymia gene.”

Genes related to serotonin and dopamine regulation may contribute to abnormal mood regulation and emotional reactivity

Brain Chemistry and Function

Neurochemical imbalances are believed to play a significant role:

Fluctuations in neurotransmitters such as serotonin, dopamine, and norepinephrine can disrupt mood stability

Functional MRI scans in mood disorder patients show altered activity in brain regions associated with emotional regulation, such as the amygdala and prefrontal cortex

These chemical imbalances may affect an individual’s ability to maintain emotional equilibrium in response to everyday stressors

Hormonal and Developmental Factors

Hormonal changes can contribute to the onset of cyclothymia, especially during:

Puberty

Pregnancy

Menstrual cycles

Perimenopause

These transitions may destabilise mood regulation, particularly in individuals who are genetically or neurologically predisposed.

Environmental Stressors | Causes of Cyclothymia

External events can trigger the onset or worsening of symptoms:

Childhood trauma, neglect, or abuse increases vulnerability

Chronic stress in adulthood, such as from work, financial strain, or toxic relationships, can lead to dysregulation of mood over time

Sudden life changes, such as divorce or job loss, may activate dormant symptoms

Substance Use

Recreational drug use and alcohol consumption can intensify mood swings and mask underlying cyclothymic symptoms:

Stimulants may mimic hypomania, while depressants exacerbate low mood

Substance abuse often leads to misdiagnosis or delayed treatment

In summary, causes of cyclothymia are multifactorial, involving genetic susceptibility, neurochemical imbalances, and environmental triggers. A comprehensive understanding of these elements is key to recognising early signs and beginning targeted, effective treatment.

[Next: Symptoms of Cyclothymia →]

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