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Causes of Flu

Microscopic view of influenza viruses affecting human lungs

Illustration showing flu viruses targeting the lungs and alveoli, highlighting how the influenza virus spreads

Causes of Flu

The causes of flu are rooted in infection by influenza viruses, which spread through droplets released when an infected person coughs, sneezes, or talks. Flu is highly contagious and can also spread via contact with contaminated surfaces, especially in crowded places like schools, offices, and public transport.

Influenza Virus Types

There are four main types of influenza viruses:

  • Influenza A – the most common and severe; responsible for seasonal epidemics and pandemics
  • Influenza B – less widespread than A but can still cause serious outbreaks
  • Influenza C – causes mild illness and does not result in epidemics
  • Influenza D – primarily affects cattle and is not known to infect humans
  • Influenza A and B are the primary causes of seasonal flu in humans.

Mutation and Antigenic Drift

Influenza viruses constantly mutate, changing their surface proteins (haemagglutinin and neuraminidase). This process, called antigenic drift, allows the virus to evade the immune system, which is why previous exposure or vaccination may not provide full protection against future strains.

How It Spreads

Flu is mainly transmitted through:

Droplet spread, from coughing or sneezing

Surface contamination, where the virus lives for hours on doorknobs, mobile phones, and other shared items

Direct contact, such as shaking hands with an infected person

A person is most contagious in the first 3 to 5 days after symptoms begin but can spread the virus even before symptoms appear.

Seasonal Patterns

Flu outbreaks occur:

During winter months in most countries

With peaks between June and August in South Africa and between December and February in the northern hemisphere

In tropical regions, flu can circulate year-round with multiple peaks

Causes of Flu

The causes of flu are deeply connected to how easily the virus spreads and evolves. Understanding its transmission helps people take steps to protect themselves and those around them.

[Next: Symptoms of Flu →]

Causes of Common Cold
Diagnosis and Testing for Bird Flu
Treatment and Prevention of Bird Flu
Causes and Transmission of Bird Flu
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