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Causes of Gastritis

Bacterial infection in the stomach causing gastritis

An illustration showing a magnified view of bacteria inside the stomach, representing one of the leading causes of gastritis – Helicobacter pylori infection

Causes of Gastritis

The causes of gastritis vary depending on the type and severity of inflammation. Gastritis usually results from damage to the stomach’s protective lining, often triggered by irritants, infections, or autoimmune activity. Understanding what causes gastritis helps in both prevention and targeted treatment.

H. pylori Infection

Helicobacter pylori is a spiral-shaped bacterium that infects the stomach lining

It’s a leading cause of chronic gastritis worldwide

Spreads through unclean food, water, or from one person to another contact

Over time, H. pylori can weaken the mucosal barrier, causing inflammation and possibly ulcers

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Long-term use of NSAIDs like ibuprofen, naproxen, and aspirin can damage the stomach lining

These medications interfere with prostaglandins, which help maintain the stomach’s protective layer

The risk increases with higher doses or longer periods of use

Alcohol and Smoking

Excessive alcohol irritates the stomach lining and increases acid production

Smoking slows the healing of the gastric mucosa and worsens existing inflammation

Both are significant risk factors for chronic gastritis

Stress-Related Gastritis

Physical stress from major surgery, burns, or severe infections can cause acute gastritis

Sometimes called “stress ulcers,” these occur when blood flow to the stomach lining is reduced

Common in hospitalised or critically ill patients

Autoimmune Gastritis

The immune system mistakenly attacks the stomach’s parietal cells

Leads to vitamin B12 deficiency and increased risk of pernicious anaemia

Often associated with other autoimmune disorders like thyroid disease or type 1 diabetes

Bile Reflux

Occurs when bile flows back into the stomach from the small intestine

This irritates the stomach lining and contributes to chronic gastritis

May happen after gallbladder surgery or in people with gastrointestinal motility disorders

Diet and Lifestyle

Spicy foods and caffeine can worsen symptoms in some individuals, although they don’t directly cause gastritis

Irregular eating habits, high stress, or skipping meals may also contribute to symptom flare-ups

Causes of Gastritis

Recognising the causes of gastritis enables healthcare providers to recommend effective lifestyle changes and treatment plans that reduce inflammation and promote healing.

[Next: Symptoms of Gastritis →]

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