Causes of labyrinthitis are mainly linked to infections that inflame the inner ear’s labyrinth, which is essential for hearing and balance. Understanding the causes of labyrinthitis helps distinguish the different triggers and allows for timely treatment. Labyrinthitis itself is not a disease but a complication from various underlying problems. Most cases are viral, but bacterial and autoimmune causes also occur.
Viral Causes of Labyrinthitis
The most common cause of labyrinthitis is a viral infection, usually following a respiratory illness like the common cold or flu. Viruses can travel from the upper respiratory tract to the inner ear and inflame the delicate labyrinth. Influenza, herpes simplex virus (HSV), Epstein-Barr virus (EBV), mumps, and measles are common culprits. This inflammation disrupts the signals from the vestibular and cochlear nerves to the brain, leading to dizziness, vertigo, hearing loss, and imbalance.
Herpes viruses can remain dormant in the body for years before reactivating, often triggered by stress or a weakened immune system. Reactivated HSV can cause severe labyrinthitis. Because it may mimic other neurological disorders, early diagnosis is important to avoid confusion.
Bacterial and Autoimmune Causes
Bacterial labyrinthitis is less common but more severe. It happens when bacteria invade the inner ear through nearby infections, such as middle ear infections (otitis media), bacterial meningitis, or a ruptured eardrum. In children, untreated ear infections increase the risk. Bacterial labyrinthitis requires prompt treatment to avoid permanent damage.
Autoimmune labyrinthitis occurs when the immune system mistakenly attacks inner ear tissues. This rare cause resembles infectious labyrinthitis but usually accompanies other autoimmune diseases like rheumatoid arthritis or lupus. Treatment focuses on suppressing the immune response rather than fighting infection.
Other Causes and Risk Factors
Allergies can contribute indirectly by causing inflammation and congestion in the middle ear and Eustachian tube. This can lead to fluid buildup or infections that increase the risk of labyrinthitis.
Certain medications can damage the inner ear and cause symptoms like labyrinthitis. Drugs such as aminoglycoside antibiotics (e.g., gentamicin), chemotherapy agents (e.g., cisplatin), and high doses of aspirin or diuretics may harm the vestibular system. Though this damage isn’t true inflammation, it causes similar symptoms and is important to consider.
Head trauma is another cause. Injuries to the skull or ear can lead to bleeding or inflammation inside the inner ear. Sometimes, trauma opens a path for bacteria to enter, causing secondary bacterial labyrinthitis.
Systemic illnesses such as mumps and meningitis can also cause labyrinthitis. Mumps, particularly in unvaccinated populations, can damage the inner ear. Bacterial meningitis may spread to the labyrinth, often causing severe and permanent hearing and balance problems.
Influencing Factors and Prevention
Lifestyle and environmental factors don’t directly cause labyrinthitis but can increase risk. Poor immune health due to chronic illness, stress, or malnutrition makes viral infections more likely. Crowded places during flu season raise exposure risk.
Vaccinations have reduced some causes of labyrinthitis. The MMR vaccine lowers virus-induced cases. Flu vaccines also reduce respiratory infections that may lead to labyrinthitis. Public health efforts to promote vaccination and early treatment of ear infections help prevent many cases.
Summary of Causes of Labyrinthitis
Labyrinthitis has multiple causes, from common viral infections to more severe bacterial or autoimmune conditions. Viral labyrinthitis is the most common and usually less serious. Bacterial and autoimmune forms require urgent attention due to higher risks of complications. Early identification of the cause is essential for effective treatment and preventing long-term damage.


