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Complications and Recovery from Bullous Pemphigoid

Woman scratching her irritated hand while sitting on a couch

Persistent itching and skin irritation are common complications of bullous pemphigoid, a chronic autoimmune skin disorder

Complications and Recovery from Bullous Pemphigoid

Complications and recovery from bullous pemphigoid are shaped by disease severity, treatment response, and overall patient health. While most people recover well with treatment, complications of bullous pemphigoid can arise from both the disease and its long-term therapy.

One of the main complications is secondary skin infection. Open blisters can become entry points for bacteria, leading to cellulitis or more serious infections. Proper wound care, hygiene, and sometimes antibiotics are necessary to reduce this risk.

Scarring and skin thickening may occur, especially in areas with repeated blistering. Pigment changes, both lighter and darker patches, can develop during the healing process. In some cases, movement may become restricted if scarring affects areas near joints.

Steroid side effects are a significant concern in long-term treatment. These include weight gain, mood swings, osteoporosis, high blood pressure, blood sugar issues, and increased susceptibility to infection. Immunosuppressant drugs also carry a risk of liver toxicity, bone marrow suppression, or reactivation of latent infections.

Emotional effects such as anxiety, frustration, or depression are common due to chronic pain, visible skin damage, and limitations on daily life. Mental health support, counselling, or support groups can play a critical role in recovery.

Complications and Recovery from Bullous Pemphigoid

Recovery times vary. Some people respond quickly and enter remission within months, while others may require years of intermittent treatment. Flare-ups can still occur, especially during times of stress or after reducing medication, but they usually become less frequent and easier to manage over time.

Lifestyle measures to support recovery include:

  • Avoiding trauma or friction to the skin
  • Using gentle, fragrance-free skincare products
  • Keeping the skin moisturised
  • Following all medical advice for drug dosing and follow-up care

With early diagnosis, consistent management, and holistic support, most individuals with bullous pemphigoid can control the condition and enjoy a good quality of life — even if long-term treatment is needed.

Back to Overview

Symptoms of Bullous Pemphigoid
Causes of Bullous Pemphigoid
Treatment of Bullous Pemphigoid
Diagnosis of Bullous Pemphigoid

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