Complications of Antiphospholipid Syndrome
Without proper treatment, APS can lead to life-threatening complications, including organ damage, stroke, pregnancy loss, and chronic disability. Even with treatment, close monitoring is essential to manage risks. Read more about Complications of Antiphospholipid Syndrome below.
1. Deep Vein Thrombosis (DVT)
- Blood clots in the legs
- Causes pain, swelling, redness
- Can lead to long-term swelling (post-thrombotic syndrome)
2. Pulmonary Embolism (PE)
- Clot travels to the lungs
- Causes chest pain, shortness of breath, and can be fatal
3. Stroke or TIA (Mini-Stroke)
- Blood clot blocks blood flow to the brain
- Affects speech, vision, coordination, or movement
- More common in younger patients with APS
4. Pregnancy Complications
- Recurrent miscarriages
- Stillbirth
- Preterm delivery due to preeclampsia or placental insufficiency
5. Heart Valve Disease
- Abnormal thickening of heart valves
- May cause murmurs, fatigue, or heart failure
6. Kidney Damage
- Small vessel clots can impair kidney function
- May lead to high blood pressure or kidney failure
7. Catastrophic Antiphospholipid Syndrome (CAPS)
- Rare but deadly form of APS
- Rapid clotting in multiple organs
- Requires emergency treatment in ICU
- Triggers include infection, surgery, or stopping anticoagulants
Preventing Complications
- Adhere strictly to medication and INR monitoring
- Avoid prolonged immobility
- Inform all healthcare providers of your APS diagnosis
- Plan pregnancies with specialist support
With proper management, many people with APS lead long, healthy lives. Awareness, especially in women of reproductive age and people with unexplained clots, is crucial for early intervention.
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Treatment for Antiphospholipid Syndrome
Diagnosis of Antiphospholipid Syndrome


