Complications of Arthritis Without proper treatment, arthritis can lead to serious physical, emotional, and functional complications, some of which may be permanent. Learn more about the complications of arthritis below. 1. Joint Damage and Deformity 2. Loss of Mobility 3. Disability 4. Systemic Involvement (Autoimmune Arthritis) 5. Osteoporosis 6. Mental Health Struggles 7. Medication Side Effects Prevention of Complications With proper management, many people with arthritis live active, fulfilling lives. In South Africa, ongoing education and improved access to care are helping more people manage the condition successfully. 👉 End of Series | Back to Overview Blouberg Rheumatology and Arthritis Centre Rheumatologist Milnerton Causes and Types of Arthritis Diagnosis of Arthritis Treatment for Arthritis