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Diagnosis of Hepatitis B

Illustration of a woman with abdominal discomfort, test tubes, and a liver under magnification representing Hepatitis B diagnosis

Conceptual graphic showing a worried woman, blood samples, and liver imagery used to explain diagnostic methods for Hepatitis B.

Doctors use a mix of tests and checks to diagnose hepatitis B. Many people do not have symptoms, especially in the early stages. This is why regular testing is important, especially for people at higher risk. Finding hepatitis B early helps protect your health and prevent the virus from spreading to others.

How Doctors Diagnose Hepatitis B

The first step is to talk about your medical history. Doctors ask about:

  • Where you were born or lived (especially if it’s a country with many cases of hepatitis B)
  • Any family history of liver disease
  • Sexual habits, such as multiple partners
  • Use of injectable drugs
  • Past blood transfusions or dialysis
  • Work risks, like health care jobs
  • Tattoos or piercings done without proper care
  • If your mother had hepatitis B (for newborn babies)

Doctors also check for signs of liver problems, like yellow skin (jaundice) or a swollen belly. But many people with hepatitis B do not look or feel sick.

Blood Tests for Hepatitis B

The main way to confirm hepatitis B is through blood tests. These tests show if you have the virus, had it before, or are protected after vaccination.

Key Blood Markers
  1. HBsAg (Hepatitis B Surface Antigen):
    Shows you have hepatitis B now. If this stays positive after six months, it means you have chronic hepatitis B.
  2. Anti-HBs (Hepatitis B Surface Antibody):
    Shows you are protected. You either got the vaccine or recovered from a past infection.
  3. Anti-HBc (Hepatitis B Core Antibody):
    Shows you had hepatitis B at some point.
  • IgM type means recent infection.
  • IgG (total) means past or long-term infection.
  1. HBeAg (Hepatitis B e Antigen):
    Shows how active the virus is. A positive result means you can easily pass it to others.
  2. Anti-HBe (Hepatitis B e Antibody):
    Appears when your body starts fighting the virus. It means less virus in your blood.
  3. HBV DNA (Viral Load):
    Measures the amount of virus in your blood. Doctors use this to decide on treatment and track how well treatment is working.
Liver Function Tests

After hepatitis B is confirmed, doctors check:

  • ALT and AST: Liver enzymes that rise when your liver is hurt.
  • Bilirubin: High levels cause yellow skin.
  • Albumin: Low levels mean your liver is not making enough protein.
  • Prothrombin time/INR: Shows if your liver makes enough clotting factors.

These tests show how healthy your liver is.

Imaging and Liver Health Checks

Sometimes, doctors use imaging to check liver damage, especially in chronic hepatitis B:

  • Ultrasound: Checks for liver size, fat, or lumps.
  • Fibroscan (Elastography): Checks how stiff your liver is (stiffness means scarring).
  • CT or MRI scans: Used if cancer or serious liver problems are suspected.

In special cases, doctors take a small sample of liver tissue (liver biopsy) to check the amount of damage.

Who Should Be Tested for Hepatitis B

Because hepatitis B often shows no signs, certain groups should get tested:

  • People born in areas where hepatitis B is common
  • Pregnant women
  • Men who have sex with men
  • People who inject drugs
  • People living with HIV
  • People who live with someone who has hepatitis B
  • Dialysis patients and transplant recipients

All pregnant women should be screened early in pregnancy to protect their babies.

Understanding Test Results (Quick Guide)
HBsAgAnti-HBsAnti-HBcWhat It Means
+–+Current infection
–++Recovered from past infection
–+–Immune after vaccination
–––No infection, no protection
––+Possible past infection (needs more testing)

Always have your doctor explain your test results fully.

Why Early Diagnosis Matters

Finding hepatitis B early helps you:

  • Start treatment before serious liver damage
  • Avoid liver scarring (cirrhosis) or cancer
  • Protect others from getting infected
  • Plan regular liver checks
  • Know if you need vaccination or extra care after contact

In summary, diagnosing hepatitis B uses special blood tests and sometimes liver scans. Early testing leads to better health, fewer problems, and stops the virus from spreading to others.

[Next: Symptoms of Hepatitis B →]

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