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Erythema Multiforme

Forearm with red circular lesions from erythema multiforme next to various medications

A person with erythema multiforme showing red, target-like lesions on the arm alongside medications possibly linked to the reaction

Erythema Multiforme

Erythema multiforme is an acute skin condition that causes distinctive red or purple target-shaped lesions, often accompanied by itching or burning. This condition typically appears on the hands, arms, legs, and face, and in more severe cases, it can also affect the mouth, eyes, or genital areas. While the condition may look alarming, it is usually self-limiting and resolves within a few weeks.

This disorder is often triggered by infections, particularly the herpes simplex virus (HSV). It can also result from certain medications, though this is less common. There are two main types:

Erythema Multiforme Minor: which affects only the skin

Major: which also involves mucous membranes and may cause systemic symptoms

The condition is not contagious but can recur, especially in those with frequent herpes outbreaks. Episodes often follow a predictable pattern, starting with flu-like symptoms before the rash develops.

Erythema Multiforme

In South Africa, this condition may be under-recognised, especially in rural areas where skin disorders are frequently misdiagnosed. Quick identification and proper management can prevent complications and provide relief.

Understanding this condition helps in early detection, accurate treatment, and avoiding unnecessary anxiety about its appearance.

[Next: Causes of Erythema Multiforme →]

Complications of Erythema Multiforme
Treatment of Erythema Multiforme
Erythema Nodosum
Diagnosis and Evaluation of Bone Cysts
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