Symptoms of Cushing’s Syndrome

Symptoms of Cushing’s Syndrome

Symptoms of Cushing’s syndrome can affect nearly every part of the body, making it a particularly difficult condition to diagnose. The impact of excess cortisol extends to physical appearance, emotional well-being, and internal organ function. While this syndrome progresses gradually, the symptoms become increasingly obvious and disruptive over time.

Physical Changes

Weight gain, particularly around the face (creating a “moon face”), upper back (“buffalo hump”), and abdomen, with slender arms and legs

Purple stretch marks (striae) on the abdomen, thighs, breasts, or arms

Facial redness

Thinning skin that bruises easily

Slow wound healing

Muscle and Bone Effects

Muscle weakness, especially in the upper arms and thighs

Osteoporosis, increasing the risk of fractures

Back and joint pain

Skin and Hair Changes

Excessive body or facial hair in women (hirsutism)

Acne and oily skin

Balding or thinning scalp hair

Reproductive and Endocrine Symptoms

Menstrual irregularities or missed periods in women

Reduced libido

Erectile dysfunction in men

Infertility in both sexes

Emotional and Cognitive Effects

Depression, anxiety, or mood swings

Poor concentration and memory loss

Sleep disturbances or insomnia

Metabolic Symptoms

High blood pressure

Elevated blood glucose levels

Increased risk of type 2 diabetes

In Children | Symptoms of Cushing’s Syndrome

Slowed growth

Obesity, especially around the midsection

In summary, symptoms of Cushing’s syndrome are broad and often mimic other health issues. Early recognition and medical evaluation are vital to prevent irreversible complications and restore hormonal balance.

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