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Symptoms of Erythrocytosis

Man holding his head and leaning on a pole, experiencing dizziness and headache—symptoms of erythrocytosis

A man showing signs of dizziness and discomfort, common symptoms in people with elevated red blood cell counts

Symptoms of Erythrocytosis

The symptoms of erythrocytosis depend on how elevated the red blood cell count becomes and whether complications arise. While erythrocytosis may be asymptomatic in its early stages, high red cell levels can cause blood to thicken, reducing oxygen flow and increasing the risk of clotting.

Common Symptoms

Headaches – Due to increased blood viscosity and reduced oxygen to the brain

Dizziness or light-headedness, especially during exertion

Blurred or double vision

Flushed skin, particularly on the face

Reddened eyes

High blood pressure

Fatigue, which may seem paradoxical despite the high oxygen-carrying capacity

Shortness of breath, especially on exertion or when lying flat

These symptoms may develop gradually or appear suddenly in cases of rapid red cell production.

Serious Symptoms and Complications

As blood thickens, the risk of clots increases. Patients may present with:

Chest pain, which may signal a heart attack

Leg swelling or pain, possibly due to deep vein thrombosis (DVT)

Stroke-like symptoms, including slurred speech, weakness, or vision changes

Bleeding or bruising, in conditions like polycythaemia vera, due to platelet abnormalities

Clot-related complications are the most dangerous consequences of erythrocytosis and require immediate medical attention.

Symptoms in Children

Though rare, erythrocytosis in children may be linked to congenital heart disease or inherited mutations. Symptoms may include:

Cyanosis (bluish skin)

Poor growth

Tiring easily

Clubbing of fingers or toes

Symptoms of Erythrocytosis In South Africa

In South Africa, many patients with chronic lung conditions may develop secondary erythrocytosis without realising it. Symptoms such as breathlessness, fatigue, or dizziness may be wrongly attributed to ageing or poor fitness. Routine screening in high-risk groups could lead to earlier diagnosis.

Public education on the signs of abnormal blood counts and routine health checks can play a vital role, particularly in regions where access to specialist care is limited.

Recognising the symptoms of erythrocytosis early can prevent serious complications and guide timely intervention before a blood clot or stroke occurs.

[Next: Diagnosis of Erythrocytosis→]

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