Treatment for DiGeorge Syndrome
There is no cure for DiGeorge syndrome, but treatment focuses on managing the individual symptoms and improving quality of life. Because the condition can affect multiple systems, treatment is usually provided by a team of specialists working together. This may include paediatricians, cardiologists, immunologists, speech therapists, and developmental experts.
One of the first priorities after diagnosis is managing heart defects. Many babies with DiGeorge syndrome need heart surgery early in life. These procedures aim to correct structural abnormalities so the heart can function properly. Recovery from surgery varies, but with good care, many children go on to lead active lives.
If calcium levels are low due to underactive parathyroid glands, calcium and vitamin D supplements are prescribed. These need to be monitored regularly to prevent seizures and muscle problems. In some cases, calcium levels may stabilise over time, but others require lifelong supplementation.
Children with immune deficiencies may need extra protection against infections. This includes avoiding live vaccines in certain cases, regular check-ups, and sometimes antibiotics or immunoglobulin therapy. In rare and severe cases, a thymus transplant or bone marrow transplant might be considered. However, these treatments are complex and only used when necessary.
Feeding and speech challenges are common, especially if a child has a cleft palate or muscle weakness in the mouth. Speech therapy helps improve clarity, while feeding therapy supports healthy nutrition. Occupational and physiotherapy also benefit children with motor delays or coordination difficulties.
Treatment for DiGeorge Syndrome
Behavioural and learning support is vital. Many children with DiGeorge syndrome benefit from individualised education plans and psychological support. Conditions like ADHD, anxiety, and social challenges can often be managed successfully with therapy and, in some cases, medication.
Parents and caregivers play a central role in managing the condition. Support groups, online forums, and counselling services can make a significant difference in navigating the daily realities of living with DiGeorge syndrome. In South Africa, some hospitals offer developmental clinics that bring multiple specialists together under one roof.
Though the journey may be complex, many individuals with DiGeorge syndrome grow into independent adults. Early treatment and consistent support can significantly improve long-term outcomes.
[Next: Complications of DiGeorge Syndrome →]
