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Treatment of Excessive Sweating

Botox injection in armpit to treat excessive sweating

Administering Botox to reduce sweat production in the underarm area

Treatment of Excessive Sweating

The treatment of excessive sweating aims to reduce sweat production, control odour, and restore confidence. Excessive sweating can often be managed successfully using topical products, medication, lifestyle changes, or advanced therapies—depending on severity and cause.

First-Line Treatments

For mild to moderate cases:

Clinical-strength antiperspirants, containing aluminium chloride. Applied at night and washed off in the morning, these block sweat ducts.

Powders, to absorb moisture and prevent fungal infections, especially for feet and underarms

Loose, breathable clothing, such as cotton or moisture-wicking fabrics

Socks changed frequently, ideally made of natural fibres or athletic materials

Over-the-counter options may be sufficient for some, but prescription products are available for more stubborn cases.

Oral Medications

When topical treatment isn’t enough:

Anticholinergics (e.g. oxybutynin or glycopyrrolate) – Reduce overall sweating by blocking nerve signals to sweat glands

Beta-blockers or benzodiazepines – Help manage stress-induced sweating

Antidepressants, if anxiety or depression is contributing

Side effects can include dry mouth, blurred vision, or urinary retention—so medical supervision is important.

Botulinum Toxin Injections

Botox injections are highly effective for underarm, hand, and foot sweating. They work by temporarily blocking the nerves that stimulate sweat glands.

Effects last 4–9 months

Treatment may be repeated as needed

Done in outpatient settings

Botox is safe and well-tolerated but may be costly or inaccessible in some public healthcare settings.

Iontophoresis

A treatment where mild electrical currents pass through water to shut down sweating in hands and feet:

Typically done several times per week

Maintenance sessions needed

Home machines are available

Iontophoresis is suitable for people who sweat heavily from their palms or soles.

Surgery

For very severe, treatment-resistant hyperhidrosis:

Endoscopic thoracic sympathectomy (ETS) – Cuts or clamps the nerves controlling sweating

Highly effective but carries risks like compensatory sweating (excessive sweating in other areas)

Surgery is a last resort and only done after all other options fail.

Treating Secondary Causes

In secondary hyperhidrosis:

Treat the underlying illness (e.g., thyroid disease, infection)

Adjust or stop any triggering medication

Manage hormonal changes in menopause with appropriate therapy

Treatment of Excessive Sweating In South Africa

Access to Botox and iontophoresis is mostly limited to urban centres or private practices. Public sector patients often rely on strong antiperspirants and oral medication. Partnerships between dermatologists and primary care providers can improve care.

The treatment of excessive sweating improves physical comfort, boosts confidence, and helps people re-engage socially. Early intervention leads to better outcomes.

[Next: Complications of Excessive Sweating →]

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