Treatment of Glandular Fever
The treatment of glandular fever focuses on relieving symptoms, managing complications, and allowing the body time to recover. Since glandular fever is caused by the Epstein-Barr virus (EBV), there is no cure or antiviral treatment that eliminates the virus. Instead, the approach is supportive, with rest and hydration forming the foundation of recovery.
Most people recover fully within a few weeks, though fatigue can persist for longer. Medical intervention is generally not required unless complications develop. Understanding how to treat the condition effectively at home and knowing when to seek help can greatly ease the recovery process.
Rest and Recovery
The cornerstone of treatment is adequate rest. Individuals with glandular fever often experience:
Profound fatigue
Muscle aches
Weakness and malaise
Rest helps the immune system focus on clearing the virus and repairing tissue inflammation. During the first two to three weeks:
Avoid school, work, or strenuous activity
Get plenty of sleep and limit social activities
Take time off sport, particularly contact or impact sports due to risk of spleen rupture
Recovery timelines vary, and people should return to normal activities gradually, based on how they feel rather than a fixed schedule.
Hydration and Nutrition
Fluids are essential during recovery to prevent dehydration, especially when fever or sore throat reduces appetite and fluid intake. Helpful strategies include:
Drinking water, diluted juice, herbal teas, or broths
Sucking on ice cubes or lollies to soothe the throat
Eating soft, easy-to-swallow foods such as yoghurt, soup, or mashed vegetables
Avoiding alcohol, which can strain the liver
Even if appetite is poor, small, regular meals support energy levels and recovery.
Managing Fever and Pain
For fever, headaches, or sore throat:
Use paracetamol or ibuprofen as directed
Avoid aspirin in children due to the risk of Reye’s syndrome
Gargle with warm salt water to reduce throat inflammation
Try throat lozenges or sprays for temporary relief
It’s important not to exceed recommended doses and to use medication only for symptom control.
Avoiding Antibiotics
Antibiotics are not effective against viruses and should not be used to treat glandular fever. If bacterial infection is suspected (e.g., secondary tonsillitis), a doctor may prescribe antibiotics. However:
Amoxicillin and ampicillin can cause a rash in people with EBV
Alternative antibiotics should be used if necessary
Rash due to antibiotics is not an allergy in these cases, but rather a reaction linked to the virus.
Medical Supervision and Monitoring
Most cases of glandular fever can be managed at home. However, medical attention is required if:
Fever exceeds 39.5°C or persists longer than a week
Swallowing becomes extremely difficult
Breathing is impaired due to swollen tonsils
Abdominal pain suggests spleen involvement
There are signs of dehydration (dry mouth, low urine output)
In rare cases, hospital admission may be needed for:
Severe tonsillar enlargement
Airway obstruction
Intravenous fluids for dehydration
Monitoring of liver function or complications
Managing Fatigue
Fatigue is the most persistent symptom and may linger for weeks or even months. Tips for managing it include:
Pacing activities and listening to the body
Breaking tasks into smaller, manageable parts
Allowing naps without oversleeping
Returning to school or work gradually, possibly with reduced hours
For some, especially students or professionals, fatigue may be frustrating or distressing. Patience and support are key.
Emotional Support and Reassurance
Glandular fever can feel overwhelming due to its long recovery and impact on daily life. Individuals may need:
Reassurance that fatigue will resolve over time
Mental health support if mood or motivation drops
Clear explanations about the illness to avoid worry
Family, employers, or educators should be informed, especially if time off or adjustments are needed.
Complementary Therapies
There is no strong evidence supporting herbal remedies or supplements for glandular fever. However, people sometimes try:
Echinacea, elderberry, or zinc lozenges
Vitamin C or D to support general immune health
Always consult a healthcare provider before starting supplements, particularly if on medication.
Summary of Home Care
| Strategy | Purpose |
| Rest and sleep | Boost recovery and immune function |
| Fluids and soft food | Prevent dehydration, reduce discomfort |
| Paracetamol/ibuprofen | Relieve pain and fever |
| Avoid sport | Prevent spleen rupture |
| Medical check-ups | Identify and treat complications early |
Conclusion | Treatment of Glandular Fever
The treatment of glandular fever revolves around rest, symptom management, and awareness of complications. With time and self-care, most people recover completely. Early recognition of danger signs and patience during the fatigue phase are the keys to a smooth recovery.


