Acromegaly is a rare hormonal disorder that usually develops in adults between the ages of 30 and 50.
It occurs when the pituitary gland makes too much growth hormone, often due to a benign tumour called a pituitary adenoma. This excess hormone causes the liver to produce too much IGF-1, leading to abnormal bone and soft tissue growth.
How Acromegaly Affects the Body
The condition progresses slowly and can often go unnoticed in its early stages. Over time, people may start to observe physical changes such as enlarged hands and feet, coarsened facial features, and joint pain. These changes may be subtle at first and are frequently mistaken for signs of ageing, arthritis, or weight gain. As a result, diagnosis is often delayed for several years after symptoms first appear.
Global Awareness and Diagnosis Delays
In South Africa, challenges such as limited access to specialised care in some public health sectors may contribute to these delays. Nonetheless, awareness is steadily increasing, and early diagnosis can significantly improve outcomes. Internationally, many patients experience similarly delayed diagnoses, emphasising the global need for better awareness and education around this condition.
Other Symptoms and Internal Complications
Aside from visible physical symptoms, individuals with acromegaly may also experience fatigue, frequent headaches, vision problems, excessive sweating, and voice deepening. Internally, vital organs like the heart, kidneys, and liver may become enlarged. This can affect their function and increase the risk of complications.
The good news is that acromegaly is manageable, especially when detected early. Treatment may involve surgery, medication, or radiation therapy, depending on the size and location of the tumour.
If you or someone you know is noticing a combination of these symptoms, speak to a healthcare provider as soon as possible.
👉 Next: What Causes Acromegaly?
Reviewed April 2025. Always consult a professional for individual guidance.
