Cushing’s Syndrome – Overview
Cushing’s syndrome is a hormonal disorder caused by prolonged exposure to high levels of cortisol in the body. Cortisol, often called the “stress hormone,” plays a vital role in regulating blood pressure, metabolism, and immune function. In this syndrome, the excessive presence of cortisol disrupts these processes, leading to a range of physical and emotional symptoms.
This condition can be endogenous (caused by the body producing too much cortisol) or exogenous (caused by external sources, such as long-term use of corticosteroid medications). The most common cause of endogenous this syndrome is a pituitary adenoma—a non-cancerous tumour that causes the pituitary gland to release too much adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce more cortisol.
Cushing’s syndrome can affect anyone but is more commonly diagnosed in women between the ages of 25 and 40. It may develop gradually, with symptoms often being mistaken for other conditions such as obesity, diabetes, or depression.
Cushing’s Syndrome
Early diagnosis and treatment are essential to prevent long-term complications, including high blood pressure, diabetes, osteoporosis, and cardiovascular disease. Treatment depends on the underlying cause and may involve medication, radiation, or surgery.
In summary, this syndrome is a serious but treatable hormonal disorder resulting from excess cortisol. Recognising its wide-ranging symptoms and addressing the cause is critical for restoring hormonal balance and overall health.
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