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Causes of Diabetic Ketoacidosis

Blood sample labelled diabetic ketoacidosis held by gloved hand

A medical professional holds a labelled test tube for diagnosing diabetic ketoacidosis in a laboratory setting.

Causes of Diabetic Ketoacidosis

Causes of diabetic ketoacidosis revolve around a critical shortage of insulin in the body, leading to dangerous metabolic changes. While most commonly linked to type 1 diabetes, diabetic ketoacidosis can also develop in people with type 2 diabetes under certain conditions. Understanding these causes helps prevent the condition and supports faster diagnosis when symptoms arise.

Missed Insulin Doses

One of the most frequent causes is skipping or forgetting insulin injections

This may be due to financial barriers, travel, misunderstanding dosage instructions, or psychological factors such as fear of hypoglycaemia

Even short periods without insulin can trigger ketone production and acidosis

Illness or Infection

Physical stress from illnesses like flu, pneumonia, or urinary tract infections increases the body’s insulin demands

At the same time, illness may suppress appetite, leading to reduced food intake and blood sugar fluctuations

Vomiting or diarrhoea can also dehydrate the body, accelerating the onset of diabetic ketoacidosis

Uncontrolled Blood Glucose

Persistently high blood sugar due to poor diabetes management raises the risk

This includes poor dietary habits, sedentary lifestyle, or inadequate glucose monitoring

High glucose levels without corresponding insulin doses result in excessive fat breakdown

New Diagnosis of Diabetes

In some cases, diabetic ketoacidosis is the first indication that a person has diabetes

This is particularly true in children and young adults who have not yet been diagnosed

Other Medical Triggers & Causes of Diabetic Ketoacidosis

Heart attacks, strokes, or pancreatitis can precipitate diabetic ketoacidosis by stressing the body

Certain medications, including corticosteroids and diuretics, may worsen insulin resistance

Emotional stress or trauma can also cause hormonal changes that contribute to DKA

Drug and Alcohol Use

Recreational drugs such as cocaine or excess alcohol consumption can trigger DKA

Alcohol can suppress appetite and impair judgement, leading to missed insulin doses

In conclusion, causes of diabetic ketoacidosis are multifaceted but usually linked to missed insulin, illness, or stress. Preventive strategies focus on education, close glucose monitoring, and prompt management of infections or other health issues.

[Next: Symptoms of Diabetic Ketoacidosis →]

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